Susan

Actual Tosymra Patient

Roller skater. Mental health advocate. People person. Susan has a heart of gold. Quality time keeps Susan going. Whether she’s fishing with her husband, leading youth groups at church, or relaxing on family vacations — she’s happiest when surrounded by loved ones. When a migraine gets in the way of plans, it can be hard to cope.

Individual results may vary.

Susan

Actual Tosymra Patient

 

Roller skater. Mental health advocate. People person. Susan has a heart of gold. Quality time keeps Susan going. Whether she’s fishing with her husband, leading youth groups at church, or relaxing on family vacations — she’s happiest when surrounded by loved ones. When a migraine gets in the way of plans, it can be hard to cope.

 

Individual results may vary.

Experiencing her first attack

Susan’s first migraine occurred in college “I wanted to cry. I was nauseous. I was very temperamental. I was getting very angry because I wanted everything to get quiet … Every move, everything just made me hurt more,” said Susan.
After a few more of these intense headaches, Susan went to a neurologist and was diagnosed with migraines.
With a name for what she was experiencing, Susan began her journey toward migraine pain relief. She was determined not to miss out on life anymore.
I was in so much pain. It was unreal. And I would just go to bed.

A support system to rely on

A migraine is different from just a regular headache.
Susan’s husband has been there for her over the years as she’s tried new medications, preventive techniques, and more.
“A migraine is different from just a regular headache and my husband is so understanding when I have to be in bed for hours,” Susan said. “And that kills me when I know we could be out doing something; just taking a walk, anything. And I’m stuck because I feel like my head is going to fall off. So, it means the world that he is there to support me. Even though he doesn’t experience them, he’s there for me.”

A toolbox she can count on

Like many who experience migraines, Susan keeps a toolbox of medication on hand in case pain should strike unexpectedly. “I am open to try to see what works. And I am open to building my arsenal of medications and my toolbox of what I need.” It wasn’t until she tried Tosymra that she felt her toolbox was complete.
“I’ve got a good setup and system of medications. I have a preventive, I have oral medications, I use injectables, and I have Tosymra, a nasal spray treatment option. I always have what I need,” Susan says. “It’s so nice with Tosymra, I can be in church, and the music will be bothering me because of a migraine. But I can just grab that Tosymra. It opens very easily, it doesn’t make a racket when you’re opening it, like trying to get a pill out of a little foil. And I can just take it and I know that I am going to be OK.”
Tosymra has helped Susan stay active and present in her daily life. “It just allows me to live my life, stay at work, and finish my day. I don’t have to call someone to come get me. Because of Tosymra, I feel prepared for my migraines. I feel prepared to face the world. I’ve got what I need.”
After the first time I used Tosymra, I laid down and 15-20 minutes later I felt better. And I was able to get up and do what I needed to do.

More patient stories

Joy

For Joy, like for so many others, the symptoms that accompany the pain are just as devastating as the migraine itself. She takes comfort in the resource she’s found in Tosymra.

Melissa

New York-based events and TV producer, nonprofit co-founder, mother of three, and wife Melissa Gerstein spent a lot of time pushing through before discovering Tosymra.

Joy

For Joy, like for so many others, the symptoms that accompany the pain are just as devastating as the migraine itself. She takes comfort in the resource she’s found in Tosymra.

Melissa

New York-based events and TV producer, nonprofit co-founder, mother of three, and wife Melissa Gerstein spent a lot of time pushing through before discovering Tosymra.

Tosymra is a prescription medicine used to treat acute migraine with or without aura in adults.

Tosymra is not used to treat other types of headaches such as hemiplegic (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines. Tosymra is not used to treat cluster headaches.

Tosymra is not used to prevent or decrease the number of migraines you have. It is not known if Tosymra is safe and effective in children under 18 years of age.

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Do not take Tosymra® if you have hemiplegic migraines or basilar migraines or to treat cluster headache.

IMPORTANT SAFETY INFORMATION
Tosymra can cause serious side effects, including heart attack and other heart problems, which may lead to death. Stop use and get emergency medical help if you have any signs of heart attack:

  • discomfort in the center of your chest that lasts for more than a few minutes or goes away and comes back
  • severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw
  • pain or discomfort in your arms, back, neck, jaw or stomach
  • shortness of breath with or without chest discomfort
  • breaking out in a cold sweat
  • nausea or vomiting
  • feeling lightheaded

Tosymra is not for people with risk factors for heart disease (high blood pressure or cholesterol, smoking, overweight, diabetes, family history of heart disease) unless a heart exam shows no problem.

Do not use Tosymra if you have:

  • history of heart problems
  • narrowing of blood vessels to your legs, arms, stomach, or kidney (peripheral vascular disease)
  • uncontrolled high blood pressure
  • hemiplegic or basilar migraines. If you are not sure if you have these, ask your provider.
  • had a stroke, transient ischemic attacks (TIAs), or problems with blood circulation
  • severe liver problems
  • taken any of the following medicines in the last 24 hours: almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, ergotamines, or dihydroergotamine. Ask your provider for a list of these medicines if you are not sure.
  • are taking certain antidepressants, known as monoamine oxidase (MAO)-A inhibitors or it has been 2 weeks or less since you stopped taking a MAO-A inhibitor. Ask your provider for a list of these medicines if you are not sure.
  • an allergy to sumatriptan or any of the components of Zembrace or Tosymra

Tell your provider about all of your medical conditions and medicines you take, including vitamins and supplements.

Tosymra can cause dizziness, weakness, or drowsiness. If so, do not drive a car, use machinery, or do anything where you need to be alert.

Tosymra may cause serious side effects including:

  • changes in color or sensation in your fingers and toes
  • sudden or severe stomach pain, stomach pain after meals, weight loss, nausea or vomiting, constipation or diarrhea, bloody diarrhea, fever
  • cramping and pain in your legs or hips; feeling of heaviness or tightness in your leg muscles; burning or aching pain in your feet or toes while resting; numbness, tingling, or weakness in your legs; cold feeling or color changes in one or both legs or feet
  • increased blood pressure including a sudden severe increase even if you have no history of high blood pressure
  • medication overuse headaches from using migraine medicine for 10 or more days each month. If your headaches get worse, call your provider.
  • serotonin syndrome, a rare but serious problem that can happen in people using Zembrace or Tosymra, especially when used with anti-depressant medicines called SSRIs or SNRIs. Call your provider right away if you have: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; or trouble walking.
  • hives (itchy bumps); swelling of your tongue, mouth, or throat
  • seizures even in people who have never had seizures before

The most common side effects of Tosymra include: tingling dizziness; feeling warm or hot, burning feeling, feeling of heaviness, feeling of pressure, flushing, feeling of tightness, numbness, application site (nasal) reactions, abnormal taste, and throat irritation.

Tell your provider if you have any side effect that bothers you or does not go away. These are not all the possible side effects of Tosymra. For more information, ask your provider.

This is the most important information to know about Tosymra but is not comprehensive. For more information, talk to your provider and read the Patient Information and Instructions for Use. You can also visit https://www.tonixpharma.com or call 1-888-869-7633.

You are encouraged to report adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.